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Hitoo Nakano Selected Research

pemirolast (Alamast)

5/2006Prophylactic effect of pemirolast, an antiallergic agent, against hypersensitivity reactions to paclitaxel in patients with ovarian cancer.
5/2004Pemirolast potently attenuates paclitaxel hypersensitivity reactions through inhibition of the release of sensory neuropeptides in rats.

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Hitoo Nakano Research Topics

Disease

18Neoplasms (Cancer)
03/2007 - 11/2002
13Ovarian Neoplasms (Ovarian Cancer)
03/2007 - 02/2002
6Hypersensitivity (Allergy)
05/2006 - 01/2004
4Pre-Eclampsia (Preeclampsia)
05/2008 - 10/2005
3Carcinoma (Carcinomatosis)
07/2005 - 02/2002
3Breast Neoplasms (Breast Cancer)
07/2005 - 11/2002
3Edema (Dropsy)
08/2004 - 01/2004
2Hypoxia (Hypoxemia)
04/2007 - 07/2005
2Adenocarcinoma
10/2005 - 08/2004
2Hypotension (Low Blood Pressure)
07/2005 - 01/2004
2Amenorrhea
12/2004 - 09/2002
1Pulmonary Hypertension
02/2012
1Stillbirth
05/2008
1Spontaneous Abortion (Miscarriage)
05/2008
1Hypertension (High Blood Pressure)
04/2008
1Necrosis
08/2007
1Ketosis
08/2007
1Pathologic Complete Response
07/2007
1Fetal Distress
07/2007
1Essential Hypertension
06/2007
1Placenta Previa
12/2006
1Hemorrhage
12/2006
1Uterine Neoplasms (Uterine Cancer)
12/2006
1Hydatidiform Mole (Molar Pregnancy)
12/2006
1congenital Chylothorax
01/2006
1Hydrothorax
01/2006
1Chylothorax
01/2006
1Cardiovascular Diseases (Cardiovascular Disease)
09/2005
1Flushing
07/2005
1Urticaria (Hives)
07/2005
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/2005
1Obesity
07/2005
1Uterine Cervical Neoplasms (Cancer of the Cervix)
06/2005

Drug/Important Bio-Agent (IBA)

7Paclitaxel (Taxol)FDA LinkGeneric
05/2006 - 01/2004
4AntigensIBA
03/2007 - 06/2005
4Histamine (Histamine Dihydrochloride)FDA Link
07/2005 - 01/2004
4Antineoplastic Agents (Antineoplastics)IBA
08/2004 - 12/2003
3N-Formylmethionine Leucyl-PhenylalanineIBA
05/2008 - 10/2005
3Reactive Oxygen Species (Oxygen Radicals)IBA
05/2008 - 10/2005
3Superoxides (Superoxide)IBA
05/2008 - 10/2005
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2008 - 05/2003
3Biological ProductsIBA
03/2007 - 03/2004
3Peptides (Polypeptides)IBA
05/2006 - 01/2004
3Proteins (Proteins, Gene)FDA Link
01/2006 - 03/2002
3lysophosphatidic acidIBA
07/2005 - 03/2003
3Interleukin-8 (Interleukin 8)IBA
07/2003 - 07/2002
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2003 - 02/2002
2NG-Nitroarginine Methyl Ester (L-NAME)IBA
04/2008 - 10/2005
2InterleukinsIBA
08/2007 - 07/2002
2GasesIBA
04/2007 - 07/2005
2Biomarkers (Surrogate Marker)IBA
03/2007 - 12/2006
2pemirolast (Alamast)FDA Link
05/2006 - 05/2004
2Carboplatin (JM8)FDA LinkGeneric
05/2006 - 07/2005
2Anti-Allergic Agents (Antiallergic Agents)IBA
05/2006 - 05/2004
2Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2005 - 09/2005
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2005 - 08/2004
2GlucocorticoidsIBA
07/2005 - 01/2004
2Oxygen (Dioxygen)IBA
07/2005 - 07/2004
2Heparin-binding EGF-like Growth Factor (HB-EGF)IBA
07/2005 - 08/2004
2Estrogens (Estrogen)FDA Link
04/2005 - 08/2004
2Anti-Bacterial Agents (Antibiotics)IBA
02/2005 - 07/2002
2Gonadotropin-Releasing Hormone (GnRH)FDA Link
12/2004 - 09/2002
2Substance PIBA
08/2004 - 07/2004
2Cisplatin (Platino)FDA LinkGeneric
08/2004 - 11/2002
2Pharmaceutical PreparationsIBA
03/2004 - 11/2002
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
02/2012
1Polychlorinated Biphenyls (PCBs)IBA
05/2008
1Insulin (Novolin)FDA Link
08/2007
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
08/2007
1DNA (Deoxyribonucleic Acid)IBA
12/2006
1CalponinsIBA
09/2006
1Therapeutic UsesIBA
09/2006
1Immunoglobulin G (IgG)IBA
01/2006
1Immunoglobulins (Immunoglobulin)IBA
01/2006
1AlbuminsIBA
01/2006
1Immunoglobulin A (IgA)IBA
01/2006
1Immunoglobulin M (IgM)IBA
01/2006
1Superoxide DismutaseIBA
10/2005
1VimentinIBA
10/2005
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
10/2005
1CatalaseIBA
10/2005
1Peroxynitrous Acid (Peroxynitrite)IBA
10/2005
1NitritesIBA
10/2005
1Estradiol (Delestrogen)FDA LinkGeneric
09/2005
1DisintegrinsIBA
07/2005
1LigandsIBA
07/2005
1Epidermal Growth Factor (EGF)IBA
07/2005
1Heparin (Liquaemin)FDA LinkGeneric
07/2005
1Metalloproteases (Metalloproteinases)IBA
07/2005
1Fas Ligand Protein (Fas Ligand)IBA
06/2005
1Conjugated (USP) Estrogens (Premarin)FDA Link
04/2005

Therapy/Procedure

6Therapeutics
08/2007 - 09/2002
5Drug Therapy (Chemotherapy)
05/2006 - 11/2002
3Premedication
07/2005 - 01/2004
2Adjuvant Chemotherapy
07/2005 - 08/2004
1Induced Abortion (Induced Abortions)
05/2008
1Cesarean Section (Caesarean Section)
07/2007
1Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
07/2007
1Hysterotomy
12/2006
1Ovariectomy (Oophorectomy)
07/2005